Discover how BOND RX can help you meet your goals

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Explore Your Ideas

Fully automate IHC, ISH and emerging tests. The incredibly flexible BOND RX gives you the freedom to discover. BOND RX customization has resulted in researchers successfully automating a wide range of technologies – from well established techniques to new frontiers of molecular histopathology and beyond.

Use your preferred markers

Fully open reagents for your ideal IHC antibody and ISH probe.

Create your own detection system

Hand-pick the components you need

Design the protocols you need

Flexible protocol editing

Automate Your Tests

Rat Testis - TSA Fluorescence Multiplexing

SMA / Vimentin / TNP2 (RNA) / DAPI

NRG1 (Brown) and ERBB3 (Red) detection in human breast

Stained using the RNAscope 2.5 LS Duplex Reagent Kit and BOND RX System

Adenocarcinoma of the lung

Stained using Kreatech ALK (2p23) Break on BOND RX using BOND FISH Kit

Chromoplex

P504S (Red) and HMW CK (DAB)

IHC staining on tonsil

Stained using CD3 (LN10) using BOND Polymer Refine Detection

BOND Polymer Double Staining Ki67 (red) and CD3 (DAB) on Human Tonsil

PD-L1 in Human Head and Neck Sqamous Cell Carcinoma

Stained using the Affymetrix ViewRNA® eZ-L Assay on BOND RX System

Multiplexed IF stain of prostate cancer cell

Stained using RareCyte IF protocol and BOND RX System

  • Create your own protocols or customise existing templates
  • Configure consecutive reagent steps
  • Insert any number of wash steps (or none) between reagents
  • Insert reagents of your choice
  • Choose to use no marker-dispensing step (if preferred to do off-board)
  • Selected protocol steps can be set to exact incubation times – includes duplicates
  • Choose the right temperature template for you

BOND Research Detection offers researchers the ability to tailor applications and fully automate staining for ease of use. This open detection system consists of six standard 30 mL open containers in a reagent tray. The tray is registered on BOND like any other detection system (one barcode only), but each of the containers can be configured with reagent of the user‘s choice.

Experience the freedom of choice with BOND RX. Truly open reagents let you use your preferred ancillaries, antibodies, probes and chromogens.

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ABOUT US


Leica Biosystems (LeicaBiosystems.com) is a global leader in workflow solutions and automation, integrating each step in the workflow from biopsy to diagnosis. Our mission of "Advancing Cancer Diagnostics, Improving Lives" is at the heart of our corporate culture. Our easy-to-use and consistently reliable offerings help improve workflow efficiency and diagnostic confidence.

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BOND RX Target and Tests

  • IHC: Immunohistochemistry
  • CISH: Chromogenic In Situ Hybridization>
  • FISH: Fluorescent In Situ Hybridization
  • TSA: Tyramide Signal Amplification
  • LNA: Locked Nucleic Acid
  • TUNEL: Terminal deoxynucleotidyl transferase dUTP
  • nick end labeling assay
  • CTC: Circulating Tumor Cells
  • IF: Immunofluorescence
  • miRNA: microRNA
  • bDNA: Branched DNA Assays
  • Multiplex Assays: IF, IHC, CISH, FISH

Third Party Assays

  • ACD RNAscope Assays (single and multiplex)
  • Affymetrix ViewRNA eZ-L Assays
  • Rarecyte AccuCyte CTC IF & IHC Assay

Available from Leica Biosystems

  • Polymer Detection (DAB and Red)
  • Chromoplex (Dual Red Brown)
  • Kreatech Customizable CISH and FISH probes
  • Novocastra IHC antibodies and ISH probes